One woman physician. A group of talented midwives. A deadly disease spreading. 1849. Dr. Nora Gibson is the only female surgeon in London. In all of England, even. After earning her medical degree and overcoming the prejudice of those who wished to see her fail, she's finally earned her place at the Great Queen Street Hospital alongside her newlywed husband and her eccentric but ailing adoptive father, the great Dr. Horace Croft. But peace is hard to come by as a physician, and for one like Nora, it's almost impossible. When Nora takes up the fight to bring midwives into the medical field, her already fragile reputation comes under fire by colleagues and London society itself. And if the possibility of losing her rights to practice medicine wasn't enough, a dangerous enemy has made itself the deadliest cholera epidemic in over a century. It's a swift disease that wreaks havoc and tragedy across the city, especially amongst the working classes, and Nora will do anything she can to help. Soon, she finds herself on the frontlines of the disease, and as those around her begin to fall, she'll have to find the strength to stand alone and maintain her greatest to save lives. Whether she'll make it through, though, is up to fate.